Is Operator - VB.Net

The Is operator checks if the run-time type of an expression result is compatible with a given type.
This is frequently used in conjunction with the TypeOf operator.

Dim oDataGridViewCell As System.Windows.Forms.DataGridViewCell 
oDataGridViewCell = Me.dgrDataGridView.Rows(e.RowIndex).Cells(e.ColumnIndex) 

If (TypeOf oDataGridViewCell Is System.Windows.Forms.DataGridViewCheckBoxCell) Then 

C# Equivalent

The equivalent operator in C# is the typeof Operator