Versions
| Visual Studio | Office Versions | .NET Library | Runtime |
| Visual Studio 2022 | Office 365, Office 2021, Office 2019 | .NET 6.0 | 2010 VSTO Runtime (v4) |
| Visual Studio 2019 | Office 365, Office 2019, Office 2016 | .NET 5.0 | 2010 VSTO Runtime (v4) |
| Visual Studio 2017 | Office 365, Office 2016, Office 2013 | .NET Framework 4.8 | 2010 VSTO Runtime (v4) |
| Visual Studio 2015 | Office 2016, Office 2013, Office 2010 | .NET Framework 4.7 | 2010 VSTO Runtime (v4) |
| Visual Studio 2013 | Office 2013, Office 2010 | .NET Framework 4.6 | 2010 VSTO Runtime (v4) |
| Visual Studio 2012 | Office 2013, Office 2010 | .NET Framework 4.5 | 2010 VSTO Runtime (v4) |
| Visual Studio 2010 | Office 2010, Office 2007 | .NET Framework 4.0 | 2010 VSTO Runtime (v4) |
| Visual Studio 2008 | Office 2007, Office 2003 | .NET Framework 3.5 | 2005 VSTO Runtime (v3) |
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